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Domuz Miyokard Enfarktüsü Modelinde Kardiyoaktif Terapötiklerin Verilmesi
JoVE Journal
Medicine
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JoVE Journal Medicine
Delivery of Cardioactive Therapeutics in a Porcine Myocardial Infarction Model
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Domuz Miyokard Enfarktüsü Modelinde Kardiyoaktif Terapötiklerin Verilmesi

Türkçe

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945 Views

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07:20 min

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February 10, 2023

DOI:

10.3791/64177-v

DOI:
10.3791/64177-v

•

07:20 min
February 10, 2023

•

13 Views
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1Centre for Heart Research, The Westmead Institute for Medical Research,The University of Sydney, 2Department of Cardiology,Westmead Hospital, 3Sydney Imaging, Core Research Facility,The University of Sydney, 4Department of Cardiothoracic Surgery,Liverpool Hospital

Summary

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Bu protokol, bir domuz modelinde kardiyoaktif terapötik ajanların uygulanmasının üç yöntemini açıklamaktadır. Dişi kara ırkı domuzları, (1) torakotomi ve transepikardiyal enjeksiyon, (2) kateter bazlı transendokardiyal enjeksiyon veya (3) juguler ven ozmotik mini pompa yoluyla intravenöz infüzyon yoluyla tedavi gördü.

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Cite this Article

Selvakumar, D., Wilkie, E., Deshmukh, T., Ravindran, D., Kotake, Y., Lu, J., Barry, T., Tran, V., Paterson, H., Hing, A., Campbell, T., Kumar, S., Kizana, E., Chong, J. J. H. Delivery of Cardioactive Therapeutics in a Porcine Myocardial Infarction Model. J. Vis. Exp. (192), e64177, doi:10.3791/64177 (2023).

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