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16:02 min
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February 10, 2023
DOI:
1Office of Research and Development, Center for Computational Toxicology and Exposure, Scientific Computing and Data Curation Division,U.S. Environmental Protection Agency, 2Oak Ridge Institute for Science and Education, 3Swenson College of Science and Engineering, Department of Biology,University of Minnesota Duluth, 4University of Wisconsin-Madison Aquatic Sciences Center, 5General Dynamics Information Technology,Research Triangle Park, 6Office of Research and Development, Center for Computational Toxicology and Exposure, Great Lakes Toxicology and Ecology Division,U.S. Environmental Protection Agency
Summary
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ここでは、米国環境保護庁の配列アライメントを利用して種感受性を予測する(SeqAPASS)ツールの最新バージョンを利用するためのプロトコルを紹介します。このプロトコルは、タンパク質の保存を迅速に分析し、種全体の化学物質感受性のカスタマイズ可能で簡単に解釈可能な予測を提供するためのオンラインツールの適用を示しています。
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Cite this Article
Vliet, S. M. F., Hazemi, M., Blatz, D., Jensen, M., Mayasich, S., Transue, T. R., Simmons, C., Wilkinson, A., LaLone, C. A. Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation. J. Vis. Exp. (192), e63970, doi:10.3791/63970 (2023).
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