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Untersuchungen von Chaperon-Cochaperon-Interaktionen mit homogenem Bead-based Assay

JoVE Journal
Biochemistry

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JoVE Journal Biochemistry

Studies of Chaperone-Cochaperone Interactions using Homogenous Bead-Based Assay

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Untersuchungen von Chaperon-Cochaperon-Interaktionen mit homogenem Bead-based Assay

2,536 Views

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06:51 min

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July 21, 2021

DOI:

10.3791/62762-v

DOI:

10.3791/62762-v

•

06:51 min

July 21, 2021

•

6 Views

Lisha Wang, Liza Bergkvist, Rajnish Kumar², Bengt Winblad³, Pavel F. Pavlov

¹Department of Neuroscience Care and Society, Division of Neurogeriatrics,Karolinska Institutet, ²Department of Pharmaceutical Engineering & Technology,Indian Institute of Technology (BHU), ³Theme Inflammation and Aging,Karolinska University Hospital

Tags

Chaperone-cochaperone Interactions Hsp90 FKBP51 FKBP52 Homogeneous Bead-based Assay High-throughput Screening Inhibitors Alzheimer’s Disease Cancer Autoimmune Disease TPR Domain Donor And Acceptor Beads Hsp90 Peptide Acceptor Beads Conjugation Glutathione Donor Beads GSTFKBP51 DMSO

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