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05:47 min
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September 23, 2021
DOI:
1Department of Psychiatry and Psychotherapy, Medical Center – University of Freiburg, Faculty of Medicine,University of Freiburg, 2Berta-Ottenstein-Programme for Clinician Scientists, Faculty of Medicine,University of Freiburg, 3Centre National de la Recherche Scientifique (CNRS),Université de Strasbourg, Institut des Neurosciences Cellulaires et Intégratives, 4Department of Stereotactic and Functional Neurosurgery, Medical Center – University Freiburg, Faculty of Medicine,University of Freiburg, 5Center for Basics in Neuromodulation, Faculty of Medicine,University of Freiburg
Summary
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Il modello murino di disperazione cronica (CDM) della depressione consiste in sessioni di nuoto forzate ripetitive e un'altra fase di nuoto ritardata come lettura. Rappresenta un modello idoneo per l'induzione di uno stato depressivo cronico stabile per almeno 4 settimane, modificabile per valutare interventi di trattamento subcronico e acuto.
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Cite this Article
Vestring, S., Serchov, T., Normann, C. Animal Models of Depression - Chronic Despair Model (CDM). J. Vis. Exp. (175), e62579, doi:10.3791/62579 (2021).
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