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Animal Models of Depression – Chronic Despair Model (CDM)
JoVE Journal
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JoVE Journal Davranış
Animal Models of Depression – Chronic Despair Model (CDM)

Animal Models of Depression – Chronic Despair Model (CDM)

6,500 Views

05:47 min

September 23, 2021

DOI:

05:47 min
September 23, 2021

39 Views
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The chronic despair mouse model (CDM) of depression consists of repetitive forced swim sessions and another delayed swim phase as a read-out. It represents a suitable model for induction of a chronic depressive-like state stable for at least 4 weeks, amendable to evaluate subchronic and acute treatment interventions.

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