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標的ナノ粒子の研究のための乳癌の同質性マウスモデルからの原発癌関連線維芽細胞の分離
JoVE Journal
Cancer Research
This content is Free Access.
JoVE Journal Cancer Research
Isolation of Primary Cancer-Associated Fibroblasts from a Syngeneic Murine Model of Breast Cancer for the Study of Targeted Nanoparticles
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標的ナノ粒子の研究のための乳癌の同質性マウスモデルからの原発癌関連線維芽細胞の分離

日本語

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4,797 Views

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08:02 min

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May 14, 2021

DOI:

10.3791/62504-v

DOI:
10.3791/62504-v

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08:02 min
May 14, 2021

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, , , , , ,
1Istituti Clinici Scientifici Maugeri IRCCS, 2Dipartimento di Scienze Biomediche e Cliniche “L. Sacco”,Università di Milano, 3Dipartimento di Biotecnologie e Bioscienze,Università di Milano-Bicocca

Summary

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本論文は、三重陰性乳癌の同種マウスモデルからの原発性癌関連線維芽細胞の単離と培養と、腫瘍微小環境を標的とするように設計された新規ナノ粒子の前臨床試験への応用を目的とする。

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Cite this Article

Truffi, M., Sitia, L., Sevieri, M., Bonizzi, A., Rizzuto, M. A., Mazzucchelli, S., Corsi, F. Isolation of Primary Cancer-Associated Fibroblasts from a Syngeneic Murine Model of Breast Cancer for the Study of Targeted Nanoparticles. J. Vis. Exp. (171), e62504, doi:10.3791/62504 (2021).

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