Screening Peptides that Activate MRGPRX2 using Engineered HEK Cells

Shammy Raj; Lei Lu; Larry  D. Unsworth

doi:10.3791/62448

Journal

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Immunology and Infection

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Detección de péptidos que activan MRGPRX2 utilizando células HEK modificadas

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Immunology and Infection
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JoVE Journal Immunology and Infection

Screening Peptides that Activate MRGPRX2 using Engineered HEK Cells

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Detección de péptidos que activan MRGPRX2 utilizando células HEK modificadas

2,304 Views

•

12:38 min

•

November 06, 2021

DOI:

10.3791/62448-v

DOI:

10.3791/62448-v

•

12:38 min

November 06, 2021

•

8 Views

Shammy Raj¹, Lei Lu², Larry D. Unsworth¹

¹Department of Chemical and Materials Engineering, Donadeo Innovation Centre for Engineering,University of Alberta, ²School of Life Science and Engineering,Southwest Jiaotong University

Summary

Se describen técnicas para generar una biblioteca de péptidos cortos que pueden activar los mastocitos a través del receptor MRGPRX2. Las técnicas asociadas son fáciles, económicas y se pueden extender a otros receptores celulares.

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Detección de péptidos que activan MRGPRX2 utilizando células HEK modificadas

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Summary

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