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Human Ex vivo Wound Model and Whole-Mount Staining Approach to Accurately Evaluate Skin Repair
JoVE Journal
Developmental Biology
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JoVE Journal Developmental Biology
Human Ex vivo Wound Model and Whole-Mount Staining Approach to Accurately Evaluate Skin Repair

Human Ex vivo Wound Model and Whole-Mount Staining Approach to Accurately Evaluate Skin Repair

English

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6,066 Views

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07:32 min

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February 17, 2021

DOI:

10.3791/62326-v

DOI:
10.3791/62326-v

•

07:32 min
February 17, 2021

•

31 Views
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1Centre for Atherothrombosis and Metabolic Disease, Hull York Medical School,University of Hull

Summary

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Here we demonstrate an optimized technique for assessing wound repair using ex vivo human skin combined with a whole-mount staining approach. This methodology provides a pre-clinical platform for the evaluation of potential wound therapies.

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Cite this Article

Wilkinson, H. N., Kidd, A. S., Roberts, E. R., Hardman, M. J. Human Ex vivo Wound Model and Whole-Mount Staining Approach to Accurately Evaluate Skin Repair. J. Vis. Exp. (168), e62326, doi:10.3791/62326 (2021).

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