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Determinação semi-quantitativa da densidade do neurônio dopaminérgico na Substantia Nigra dos Modelos de Roedores usando análise automatizada de imagem
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February 02, 2021
DOI:
1Krembil Research Institute, Toronto Western Hospital,University Health Network, 2Department of Laboratory Medicine and Pathobiology,University of Toronto, 3Department of Surgery, Division of Neurosurgery,University of Toronto, 4Department of Medicine, Division of Neurology,University of Toronto, 5Department of Medicine, Division of Neurology, Edmond J. Safra Program in Parkinson’s Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital,University Health Network, 6Tanz Centre for Research in Neurodegenerative Diseases,University of Toronto
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Aqui apresentamos um método automatizado para determinação semi-quantitativa do número de neurônio dopaminérgico na substantia nigra pars compacta.
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O'Hara, D. M., Kapadia, M., Ping, S., Kalia, S. K., Kalia, L. V. Semi-Quantitative Determination of Dopaminergic Neuron Density in the Substantia Nigra of Rodent Models using Automated Image Analysis. J. Vis. Exp. (168), e62062, doi:10.3791/62062 (2021).
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