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Determinazione semi-quantitativa della densità neuronale dopaminergica nella Substantia Nigra dei modelli di roditori utilizzando l'analisi automatizzata delle immagini
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February 02, 2021
DOI:
1Krembil Research Institute, Toronto Western Hospital,University Health Network, 2Department of Laboratory Medicine and Pathobiology,University of Toronto, 3Department of Surgery, Division of Neurosurgery,University of Toronto, 4Department of Medicine, Division of Neurology,University of Toronto, 5Department of Medicine, Division of Neurology, Edmond J. Safra Program in Parkinson’s Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital,University Health Network, 6Tanz Centre for Research in Neurodegenerative Diseases,University of Toronto
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Qui presentiamo un metodo automatizzato per la determinazione semi-quantitativa del numero di neuroni dopaminergici nella substantia nigra pars compacta del ratto.
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O'Hara, D. M., Kapadia, M., Ping, S., Kalia, S. K., Kalia, L. V. Semi-Quantitative Determination of Dopaminergic Neuron Density in the Substantia Nigra of Rodent Models using Automated Image Analysis. J. Vis. Exp. (168), e62062, doi:10.3791/62062 (2021).
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