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Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction

Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction

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6,253 Views

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07:47 min

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September 26, 2020

DOI:

10.3791/61675-v

DOI:
10.3791/61675-v

•

07:47 min
September 26, 2020

•

3 Views
,
1The University of Sydney, 2University of Technology Sydney (UTS), 3The Royal North Shore Hospital, 4University Hospital of Wales

Summary

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This protocol aims to transplant a 3D bioprinted patch onto the epicardium of infarcted mice modeling heart failure. It includes details regarding anesthesia, the surgical chest opening, permanent ligation of the left anterior descending (LAD) coronary artery and application of a bioprinted patch onto the infarcted area of the heart.

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Cite this Article

Roche, C. D., Gentile, C. Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction. J. Vis. Exp. (163), e61675, doi:10.3791/61675 (2020).

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