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En Pathway Association Study Tool for GWAS analyser af metaboliske Pathway Information
JoVE Journal
Genetics
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JoVE Journal Genetics
A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information
DOI:

05:01 min

July 01, 2020

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Chapters

  • 00:05Introduction
  • 00:32Genome-Wide Association Study (GWAS) Data Loading
  • 00:57Load Linkage Disequilibrium (LD) Data Loading
  • 01:26Single Nucleotide Polymorphism (SNP) Assignment
  • 01:56Significant Pathway Discovery
  • 02:35Rugplot Visualization
  • 03:21Results: Representative GWAS Analyses of Metabolic Pathway Information
  • 04:21Conclusion

Summary

Automatic Translation

Ved at køre Pathway Association Study Tool (PAST), enten gennem Shiny ansøgning eller gennem R-konsollen, kan forskerne få en dybere forståelse af den biologiske betydning af deres genom-dækkende forening undersøgelse (GWAS) resultater ved at undersøge de metaboliske veje involveret.

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