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Inducción de lesión cerebral axonal difusa en ratas basada en aceleración rotacional
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06:14 min
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May 09, 2020
DOI:
1Division of Anesthesia and Critical Care, Soroka University Medical Center and the Faculty of Health Sciences,Ben-Gurion University of the Negev, 2Department of Neurosurgery, Soroka University Medical Center and the Faculty of Health Sciences,Ben-Gurion University of the Negev, 3Department of Anesthesiology,Yale University School of Medicine, 4Recanati School for Community Health Professions, Faculty of Health Sciences,Ben-Gurion University of the Negev, 5Department of microbiology and immunology, Faculty of Health Sciences,Ben-Gurion University of the Negev
Summary
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Este protocolo valida un modelo de roedor fiable, fácil de realizar y reproducible de lesión axonal difusa cerebral (DAI) que induce daño generalizado a la materia blanca sin fracturas o contusiones de cráneo.
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Cite this Article
Frank, D., Melamed, I., Gruenbaum, B. F., Grinshpun, J., Kuts, R., Shvartsur, R., Azab, A. N., Assadi, M. H., Vinokur, M., Boyko, M. Induction of Diffuse Axonal Brain Injury in Rats Based on Rotational Acceleration. J. Vis. Exp. (159), e61198, doi:10.3791/61198 (2020).
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