需要订阅 JoVE 才能查看此. 登录或开始免费试用。
Induction of Diffuse Axonal Brain Injury in Rats Based on Rotational Acceleration
8,290 Views
•
06:14 min
•
May 09, 2020
DOI:
1Division of Anesthesia and Critical Care, Soroka University Medical Center and the Faculty of Health Sciences,Ben-Gurion University of the Negev, 2Department of Neurosurgery, Soroka University Medical Center and the Faculty of Health Sciences,Ben-Gurion University of the Negev, 3Department of Anesthesiology,Yale University School of Medicine, 4Recanati School for Community Health Professions, Faculty of Health Sciences,Ben-Gurion University of the Negev, 5Department of microbiology and immunology, Faculty of Health Sciences,Ben-Gurion University of the Negev
Summary
Automatically generated
This protocol validates a reliable, easy-to-perform and reproducible rodent model of brain diffuse axonal injury (DAI) that induces widespread white matter damage without skull fractures or contusions.
Read Article
Cite this Article
Frank, D., Melamed, I., Gruenbaum, B. F., Grinshpun, J., Kuts, R., Shvartsur, R., Azab, A. N., Assadi, M. H., Vinokur, M., Boyko, M. Induction of Diffuse Axonal Brain Injury in Rats Based on Rotational Acceleration. J. Vis. Exp. (159), e61198, doi:10.3791/61198 (2020).
Copy