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诱导大鼠心肌梗死的半微创方法及独立工作心脏系统对心脏功能的评估
JoVE Journal
Medicine
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JoVE Journal Medicine
Semi-Minimal Invasive Method to Induce Myocardial Infarction in Rats and the Assessment of Cardiac Function by an Isolated Working Heart System
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诱导大鼠心肌梗死的半微创方法及独立工作心脏系统对心脏功能的评估

DOI:
10.3791/61033-v

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08:01 min

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June 11, 2020

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, , , , , , , , ,
1Ludwig-Boltzmann-Institute for Cardiovascular Research at the Center for Biomedical Research,Medical University of Vienna, 2Concept & Ideation, Electrical Sector/EMEA/Power Distribution Division,Eaton Industries (Austria) GmbH, 3Vetfarm and Clinical Unit for Herd Health Management in Ruminants, Clinic for Ruminants,Vetmeduni Vienna

Chapters

  • 00:04Introduction
  • 01:29Induction of Myocardial Ischemia
  • 03:41Echocardiography Measurements and Organ Harvesting
  • 05:03Ex Vivo Hemodynamic Measurements via a Working Heart System
  • 06:15Results: Effects of Remote Ischemic Conditioning
  • 07:17Conclusion

Summary

Automatic Translation

Automatic Translation

本文提出了一种使用微创方法在大鼠中进行心肌缺血和随后的慢性再灌注的有效方法。此外，通过回声心动图和孤立的工作心脏方法评估大鼠左心室造影功能。

Tags

Keywords: Myocardial InfarctionRat ModelSemi-minimal InvasiveIsolated Working Heart SystemLeft Anterior Descending Artery OcclusionIschemia-reperfusionCardiac Function Assessment

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