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Synthese van informatiedragende Peptoids en hun reeks-geleide Dynamische Covalent Zelfassemblage
JoVE Journal
Chemistry
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JoVE Journal Chemistry
Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
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Synthese van informatiedragende Peptoids en hun reeks-geleide Dynamische Covalent Zelfassemblage

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6,827 Views

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09:34 min

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February 06, 2020

DOI:

10.3791/60442-v

DOI:
10.3791/60442-v

•

09:34 min
February 06, 2020

•

4 Views
, ,
1Department of Chemical Engineering,University of Michigan, 2Department of Chemical Engineering,Monash University, 3Department of Materials Science and Engineering,Monash University

Summary

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Een protocol wordt gepresenteerd voor de synthese van informatie-gecodeerde peptoid oligomeren en voor de sequentie-gerichte zelfassemblage van deze peptoids in moleculaire ladders met behulp van amines en aldehyden als dynamische covalente reactant paren en Lewis zure zeldzame aarde metalen triflates als multi-role reagentia.

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Leguizamon, S. C., Alqubati, A. F., Scott, T. F. Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly. J. Vis. Exp. (156), e60442, doi:10.3791/60442 (2020).

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