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Perspicacia mecanicista sobre el desarrollo de la fibrosis intestinal mediada por TNBS y la evaluación de los efectos inhibidores de la rapamicina
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September 12, 2019
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1Department of Molecular and Cellular Physiology,Albany Medical College, 2The IBD Center, Division of Gastroenterology, Department of Medicine,Albany Medical College, 3Department of Geriatrics, School of Medicine and Health Science,University of North Dakota, 4Department of Neuroscience and Experimental Therapeutics,Albany Medical College
Summary
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En este estudio, describimos un procedimiento detallado de fibrosis intestinal mediada por TNBS, que exhibe fisiopatología comparable a la fibrosis de Crohn. También discutimos este enfoque a la luz de los efectos inhibidores facilitados por la rapamicina sobre la fibrosis intestinal.
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Mathur, R., Alam, M. M., Zhao, X., Huang, Y., Zhu, X. Mechanistic Insight into the Development of TNBS-Mediated Intestinal Fibrosis and Evaluating the Inhibitory Effects of Rapamycin. J. Vis. Exp. (151), e60067, doi:10.3791/60067 (2019).
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