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Driedimensionaal angiogenese-assay systeem met co-Culture Spheroids gevormd door endotheliale kolonie vormende cellen en mesenchymale stamcellen
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September 18, 2019
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Driedimensionaal co-Culture spheroid-systeem voor angiogenese is ontworpen om de fysiologische angiogenese na te bootsen. Co-Culture sferoïden worden gevormd door twee humane vasculaire celprecursoren, ecfcs en MSCS, en ingebed in collageen gel. Het nieuwe systeem is effectief voor het evalueren van angiogene modulatoren en verschaft relevantere informatie aan de in vivo studie.
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Shah, S., Lee, H., Park, Y. H., Jeon, E., Chung, H. K., Lee, E. S., Shim, J. H., Kang, K. Three-dimensional Angiogenesis Assay System using Co-culture Spheroids Formed by Endothelial Colony Forming Cells and Mesenchymal Stem Cells. J. Vis. Exp. (151), e60032, doi:10.3791/60032 (2019).
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