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Developmental Biology
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人诱导多能干细胞体外生成体细胞衍生物的研究
JoVE Journal
Developmental Biology
This content is Free Access.
JoVE Journal
Developmental Biology
In Vitro Generation of Somite Derivatives from Human Induced Pluripotent Stem Cells
Please note that all translations are automatically generated.
Click here for the English version.
人诱导多能干细胞体外生成体细胞衍生物的研究
DOI:
10.3791/59359-v
•
06:21 min
•
April 25, 2019
•
Taiki Nakajima
,
Hidetoshi Sakurai
,
Makoto Ikeya
1
Department of Life Science Frontiers, Center for iPS Cells Research and Application
,
Kyoto University
,
2
Department of Clinical Application, Center for iPS Cells Research and Application
,
Kyoto University
Chapters
00:04
Title
00:58
Human Induced Pluripotent Stem Cell (iPSC) Pre-induction Preparation
02:14
Presomitic Mesoderm (PSM) and Somitic (SM) Differentiation
03:20
SM Derivative [Syndetome (SYN)] Differentiation
04:28
Results: Representative iPSC-derived Product Characterization
05:44
Conclusion
Summary
Automatic Translation
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Automatic Translation
我们在这里提出了一个方案, 分化为每个体细胞衍生物 (肌细胞, 硬化体, 皮肤和合成) 在化学定义的条件下, 这在未来的疾病建模和骨科手术中基于细胞的治疗。
Tags
Induced Pluripotent Stem Cells
IPSC
Somite Derivatives
Myotome
Dermatome
Sclerotome
Syndetome
Paraxial Mesoderm
Presomitic Mesoderm
Delta-like Protein 1
Regenerative Therapy
Disease Modeling
Musculoskeletal Disorder
Human Embryogenesis
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