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Purificación y trasplante de células progenitoras miógena derivan exosomas para mejorar la función cardiaca en ratones distróficos musculares de Duchenne
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Genetics
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JoVE Journal Genetics
Purification and Transplantation of Myogenic Progenitor Cell Derived Exosomes to Improve Cardiac Function in Duchenne Muscular Dystrophic Mice
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Purificación y trasplante de células progenitoras miógena derivan exosomas para mejorar la función cardiaca en ratones distróficos musculares de Duchenne

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5,944 Views

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08:13 min

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April 10, 2019

DOI:

10.3791/59320-v

DOI:
10.3791/59320-v

•

08:13 min
April 10, 2019

•

3 Views
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1Vascular Biology Center, Medical College of Georgia,Augusta University, 2Renji Hospital, School of Medicine,Shanghai Jiaotong University

Summary

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Aquí, presentamos un protocolo para mejorar transitoriamente la función cardiaca en ratones de la distrofia muscular de Duchenne mediante el trasplante de exosomas derivados de células progenitoras miógena normal.

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Duchenne Muscular DystrophyExosomesMyogenic Progenitor CellsCardiac FunctionEchocardiographyUltracentrifugationIntramyocardial Transplantation

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Cite this Article

Su, X., Shen, Y., Jin, Y., Jiang, M., Weintraub, N., Tang, Y. Purification and Transplantation of Myogenic Progenitor Cell Derived Exosomes to Improve Cardiac Function in Duchenne Muscular Dystrophic Mice. J. Vis. Exp. (146), e59320, doi:10.3791/59320 (2019).

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