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利用巴恩斯迷宫和困境中的破坏范式分析小鼠的空间学习和社会行为

JoVE Journal
Behavior

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JoVE Journal Behavior

Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms

Please note that all translations are automatically generated. Click here for the English version.

利用巴恩斯迷宫和困境中的破坏范式分析小鼠的空间学习和社会行为

DOI:

10.3791/58008-v

•

08:00 min

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November 17, 2018

•

James Ingersoll, Michael Moody, Robert Holland, Wesley Kuegler, Charles Murrah Jr., John Winslow, Neal Reynolds, Nathaniel Lloyd, Brian Dugan, Madalyn Hammock, Katherine Houlé, Erin Clabough

¹Department of Biology,Hampden-Sydney College, ²College of Medicine at the Medical University of South Carolina,College of South Carolina

Chapters

00:04Title
00:42Barnes Maze Testing Procedure and Data Analysis
03:08Damsel-in-Distress Testing: Exploratory Behavior and Social Responsiveness Measures and Data Analysis
06:11Results: Representative Murine Spatial Learning and Prosocial Behavior Analyses
07:32Conclusion

Summary

Automatic Translation

该协议使用巴恩斯迷宫测量空间学习和记忆。一种新的遇险损伤范式被用来评估小鼠的运动活动和亲社会行为。

Tags

Keywords: Spatial Learning Prosocial Behavior Barnes Maze Damsel-in-Distress Paradigms Behavioral Neuroscience Genetic Mutations Environmental Variables Social Behaviors Spatial Memories Mouse Model Empathy Measure Maze Testing Procedure Training Test Acclimation Video Recording Search Strategies Target Hole Ultrasonic Noise Animal Movement Tracking

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