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Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms
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Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms

Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms

13,467 Views

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08:00 min

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November 17, 2018

DOI:

10.3791/58008-v

DOI:
10.3791/58008-v

•

08:00 min
November 17, 2018

•

15 Views
, , , , , , , , , , ,
1Department of Biology,Hampden-Sydney College, 2College of Medicine at the Medical University of South Carolina,College of South Carolina

Summary

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This protocol measures spatial learning and memory using the Barnes maze. A novel Damsel-in-Distress paradigm is used to assess locomotor activity and prosocial behavior in mice.

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Spatial LearningProsocial BehaviorBarnes MazeDamsel-in-Distress ParadigmsBehavioral NeuroscienceGenetic MutationsEnvironmental VariablesSocial BehaviorsSpatial MemoriesMouse ModelEmpathy MeasureMaze Testing ProcedureTraining TestAcclimationVideo RecordingSearch StrategiesTarget HoleUltrasonic NoiseAnimal Movement Tracking

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Ingersoll, J., Moody, M., Holland, R., Kuegler, W., Murrah Jr., C., Winslow, J., Reynolds, N., Lloyd, N., Dugan, B., Hammock, M., Houlé, K., Clabough, E. Analyzing Spatial Learning and Prosocial Behavior in Mice Using the Barnes Maze and Damsel-in-Distress Paradigms. J. Vis. Exp. (141), e58008, doi:10.3791/58008 (2018).

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