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En enkel og billig analyse til måling af Ambulation i musemodeller af Muskelsvindfonden
JoVE Journal
Behavior
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JoVE Journal Behavior
A Simple and Low-cost Assay for Measuring Ambulation in Mouse Models of Muscular Dystrophy
DOI:

05:54 min

December 29, 2017

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Chapters

  • 00:05Title
  • 00:43Chamber Preparation, Muscle Activation, and Ambulation Recording
  • 01:50Video Analysis
  • 03:28Results: Analysis of mdx Ambulation and Representative Effects of Exercise
  • 05:16Conclusion

Summary

Automatic Translation

Denne protokol beskriver en fleksibel, billig system til måling af musen ambulation i en åben mark aktivitet assay. Vi viser, at en 6-minutters ambulation analysen baseret på dette system registrerer et fald i frivillig bevægelse i mdx mus og præcist adskiller forbedring i en muskel-specifikke redning af disse dyr.

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