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Paw-Print Analysis of Contrast-Enhanced Recordings (PrAnCER): A Low-Cost, Open-Access Automated Gait Analysis System for Assessing Motor Deficits
JoVE Journal
Behavior
This content is Free Access.
JoVE Journal Behavior
Paw-Print Analysis of Contrast-Enhanced Recordings (PrAnCER): A Low-Cost, Open-Access Automated Gait Analysis System for Assessing Motor Deficits

Paw-Print Analysis of Contrast-Enhanced Recordings (PrAnCER): A Low-Cost, Open-Access Automated Gait Analysis System for Assessing Motor Deficits

DOI:
10.3791/59596-v

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06:25 min

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August 12, 2019

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, , ,
1Cognitive, Linguistic & Psychological Sciences,Brown University, 2Department of Neuroscience,Brown University, 3Department of Neurosurgery, Warren Alpert Medical School,Brown University

Chapters

  • 00:04Title
  • 00:43Gait Analysis Apparatus Preparation and Animal Habituation
  • 02:06Gait Testing Procedure
  • 03:07Paw-Print Analysis of Contrast-Enhanced Recordings (PrAnCER) Automated Analysis
  • 04:52Results: Representative Accuracy of Automated Analysis and Effects of Haloperidol on Gait
  • 05:58Conclusion

Summary

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We describe a novel gait analysis system, Paw-Print Analysis of Contrast-Enhanced Recordings (PrAnCER), an open-access automated system for the quantification of gait characteristics in rats that utilizes a novel semitransparent floor to automatically quantify gait. This system was validated using the haloperidol model of Parkinson’s Disease.

Tags

Paw Print AnalysisContrast-enhanced RecordingsPrAnCERGait Analysis SystemMotor DeficitsSpinal Cord InjuryNerve DamageNeurodegenerative DiseasesNeuromuscular DisordersPlexiglass WalkwayDrafting VellumLED LightsHabituationHome CageWebcamAutomated Analysis ProgramMotor Function

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