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10:47 min
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March 02, 2018
DOI:
1Department of Neuroscience and Cell Biology,Rutgers Robert Wood Johnson Medical School, 2Center for Advanced Biotechnology and Medicine, Department of Neuroscience and Cell Biology,Rutgers Robert Wood Johnson Medical School, 3The Child Health Institute of NJ, Department of Obstetrics, Gynecology, and Reproductive Services,Rutgers Robert Wood Johnson Medical School, 4The Child Health Institute of NJ, Department of Neuroscience and Cell Biology,Rutgers Robert Wood Johnson Medical School, 5Department of Genetics,Rutgers University
Summary
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増殖、移行、および神経突起伸長はしばしば脳神経疾患で摂動など発達のプロセスします。このように、迅速かつ再現性をもって人間の iPSC 由来の Npc でこれらの神経発達のプロセスを評価するためのプロトコルを提案する.これらのプロトコルには、NPC 発育に及ぼす関連成長因子と治療の評価ができます。
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Cite this Article
Williams, M., Prem, S., Zhou, X., Matteson, P., Yeung, P. L., Lu, C., Pang, Z., Brzustowicz, L., Millonig, J. H., Dicicco-Bloom, E. Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs). J. Vis. Exp. (133), e56628, doi:10.3791/56628 (2018).
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