Journal
/
Developmental Biology
/
iPSC türetilmiş İnsan Beyin Organoids oluşturulması Erken Nörogelişimsel Bozuklukları Model
JoVE Journal
Developmental Biology
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Developmental Biology
Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders
Please note that all translations are automatically generated. Click here for the English version.

iPSC türetilmiş İnsan Beyin Organoids oluşturulması Erken Nörogelişimsel Bozuklukları Model

Türkçe

Automatically Generated

19,275 Views

•

07:40 min

•

April 14, 2017

DOI:

10.3791/55372-v

DOI:
10.3791/55372-v

•

07:40 min
April 14, 2017

•

16 Views
,
1Center for Molecular Medicine Cologne,University of Cologne, 2Institute for Biochemistry I,Medical School of University of Cologne

Summary

Automatically generated

Modeling human brain development has been hindered due to the unprecedented complexity of neural epithelial tissue. Here, a method for the robust generation of brain organoids to delineate early events of human brain development and to model microcephaly in vitro is described.

Explore More Videos

IPSCBrain OrganoidsNeurodevelopmental DisordersNeurogenesisPrimary MicrocephalyNeurospheresEHS MatrixSpinner FlaskBrain Organoid MediumOrganoid Culture

Read Article

Cite this Article

Gabriel, E., Gopalakrishnan, J. Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders. J. Vis. Exp. (122), e55372, doi:10.3791/55372 (2017).

Download .ris file

Copy

Share Video

.

Copy