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Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders
JoVE Journal
発生生物学
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JoVE Journal 発生生物学
Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders

Generation of iPSC-derived Human Brain Organoids to Model Early Neurodevelopmental Disorders

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07:40 min

April 14, 2017

DOI:

07:40 min
April 14, 2017

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概要

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Modeling human brain development has been hindered due to the unprecedented complexity of neural epithelial tissue. Here, a method for the robust generation of brain organoids to delineate early events of human brain development and to model microcephaly in vitro is described.

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