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Maus Umprogrammieren Embryonale Fibroblasten mit Transkriptionsfaktoren ein Hemogenic Programm zu induzieren
JoVE Journal
Developmental Biology
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JoVE Journal Developmental Biology
Reprogramming Mouse Embryonic Fibroblasts with Transcription Factors to Induce a Hemogenic Program

Maus Umprogrammieren Embryonale Fibroblasten mit Transkriptionsfaktoren ein Hemogenic Programm zu induzieren

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11:00 min

December 16, 2016

DOI:

11:00 min
December 16, 2016

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Summary

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The protocol described here details the induction of a hemogenic program in mouse embryonic fibroblasts via overexpression of a minimal set of transcription factors. This technology may be translated to the human system to provide platforms for future study of hematopoiesis, hematologic disease, and hematopoietic stem cell transplant.

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