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バイオコンジュゲーションとのアルタン<sup> 89</sup>のZr-DFO標識抗体
JoVE Journal
Chemistry
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JoVE Journal Chemistry
The Bioconjugation and Radiosynthesis of 89Zr-DFO-labeled Antibodies

バイオコンジュゲーションとのアルタン<sup> 89</sup>のZr-DFO標識抗体

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09:29 min

February 12, 2015

DOI:

09:29 min
February 12, 2015

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Summary

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Due to its multi-day radioactive half-life and favorable decay properties, the positron-emitting radiometal 89Zr is extremely well-suited for use in antibody-based radiopharmaceuticals for PET imaging. In this protocol, the bioconjugation, radiosynthesis, and preclinical application of 89Zr-labeled antibodies will be described.

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