Bu içeriği görüntülemek için JoVE aboneliği gereklidir. Oturum açın veya ücretsiz deneme sürümünü başlatın.
The Bioconjugation and Radiosynthesis of 89Zr-DFO-labeled Antibodies
16,681 Views
•
09:29 min
•
February 12, 2015
DOI:
Özet
Automatically generated
Due to its multi-day radioactive half-life and favorable decay properties, the positron-emitting radiometal 89Zr is extremely well-suited for use in antibody-based radiopharmaceuticals for PET imaging. In this protocol, the bioconjugation, radiosynthesis, and preclinical application of 89Zr-labeled antibodies will be described.
Read Article
Cite this Article
Zeglis, B. M., Lewis, J. S. The Bioconjugation and Radiosynthesis of 89Zr-DFO-labeled Antibodies. J. Vis. Exp. (96), e52521, doi:10.3791/52521 (2015).
Copy