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Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice
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Medicine
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JoVE Journal Medicine
Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice

Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice

English

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9,753 Views

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09:01 min

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March 10, 2015

DOI:

10.3791/52383-v

DOI:
10.3791/52383-v

•

09:01 min
March 10, 2015

•

2 Views
, ,
1The Walter and Eliza Hall Institute for Medical Research, 2The Department of Medical Biology,University of Melbourne, 3Olivia Newton-John Cancer Research Institute

Summary

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We describe methods for longitudinal monitoring of the efficacy of therapeutics for the treatment of colonic pathologies in mice using a rigid endoscope. This protocol can be readily used for the characterization of the therapeutic response of an individual tumor in live mice and also for monitoring potential disease relapse.

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Ernst, M., Preaudet, A., Putoczki, T. Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice. J. Vis. Exp. (97), e52383, doi:10.3791/52383 (2015).

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