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Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice
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March 10, 2015
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We describe methods for longitudinal monitoring of the efficacy of therapeutics for the treatment of colonic pathologies in mice using a rigid endoscope. This protocol can be readily used for the characterization of the therapeutic response of an individual tumor in live mice and also for monitoring potential disease relapse.
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Non-invasive AssessmentTherapeutic EfficacyIntestinal PathologiesEndoscopic ImagingLive MiceAnimal ModelsInflammatory Bowel DiseaseColorectal CancerPre-clinical StudiesAcute Mucosal DamageChronic ColitisColitis-associated Colon CancerSporadic Colorectal CancerSerial Endoscopic ExaminationTherapeutic ResponseHealth Monitoring
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Ernst, M., Preaudet, A., Putoczki, T. Non-invasive Assessment of the Efficacy of New Therapeutics for Intestinal Pathologies Using Serial Endoscopic Imaging of Live Mice. J. Vis. Exp. (97), e52383, doi:10.3791/52383 (2015).
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