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Tests für die Identifizierung neuer Antivirale gegen Blauzungenvirus
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Immunology and Infection
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JoVE Journal Immunology and Infection
Assays for the Identification of Novel Antivirals against Bluetongue Virus
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Tests für die Identifizierung neuer Antivirale gegen Blauzungenvirus

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13,808 Views

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12:02 min

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October 11, 2013

DOI:

10.3791/50820-v

DOI:
10.3791/50820-v

•

12:02 min
October 11, 2013

•

5 Views
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1Division of Infectious Diseases, Department of Medicine,University of Alabama at Birmingham, 2Molette Laboratory for Drug Discovery, Department of Chemistry and Biochemistry,Auburn University

Summary

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Drei Assays, einschließlich des zytopathischen Effekts (CPE)-basierte Assays, Dosis-Wirkungs-Assay und Time-of-Addition (TOA)-Assay entwickelt, optimiert, validiert und genutzt, um neue antivirale Mittel gegen Blauzungenvirus (BTV) zu identifizieren, sowie um den möglichen Mechanismus-of-Aktion (MoA) für neu identifizierten antiviralen Medikamenten zu bestimmen.

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Cite this Article

Gu, L., Schneller, S. W., Li, Q. Assays for the Identification of Novel Antivirals against Bluetongue Virus. J. Vis. Exp. (80), e50820, doi:10.3791/50820 (2013).

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