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Protein Misfolding Cyclic Amplification of Prions
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Immunology and Infection
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JoVE Journal Immunology and Infection
Protein Misfolding Cyclic Amplification of Prions

Protein Misfolding Cyclic Amplification of Prions

English

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19,319 Views

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10:12 min

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November 07, 2012

DOI:

10.3791/4075-v

DOI:
10.3791/4075-v

•

10:12 min
November 07, 2012

•

7 Views
, ,
1Department of Civil Engineering,University of Nebraska at Lincoln, 2Department of Medical Microbiology and Immunology,Creighton University

Summary

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Protein misfolding cyclic amplification (PMCA) is an in vitro assay for the study of prion conversion and strain and species barriers. It can also be used as a prion detection assay.

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Cite this Article

Saunders, S. E., Bartz, J. C., Shikiya, R. A. Protein Misfolding Cyclic Amplification of Prions. J. Vis. Exp. (69), e4075, doi:10.3791/4075 (2012).

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