Journal
/
Neuroscience
/
电检测屏幕的配对Nanoinjection和生物活性化合物的使用果蝇巨人纤维系统
JoVE Journal
Neuroscience
Author Produced
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Neuroscience
Paired Nanoinjection and Electrophysiology Assay to Screen for Bioactivity of Compounds using the Drosophila melanogaster Giant Fiber System
Please note that all translations are automatically generated. Click here for the English version.

电检测屏幕的配对Nanoinjection和生物活性化合物的使用果蝇巨人纤维系统

DOI:
10.3791/3597-v

•

09:39 min

•

April 15, 2012

•

, , , ,
1Department of Biological Sciences,Florida Atlantic University, 2Department of Chemistry & Biochemistry,Florida Atlantic University

Chapters

  • 00:02Title
  • 00:48Electrophysiology rig set-up
  • 01:18Nanoinjection set-up
  • 03:14Drosophila melanogaster preparation
  • 03:58Paired nanoinjection/electrophysiology
  • 07:35Results

Summary

Automatic Translation

Automatic Translation

迅速<em>在体内</em>分析测试neuromodulatory使用巨人光纤系统（GFS）的化合物<em>果蝇</em>描述。 nanoinjections动物的头，随着政府飞行服务队的电生理记录可以揭示生物活​​性化合物对神经或肌肉。

Tags

NanoinjectionElectrophysiology AssayScreenBioactivityCompoundsDrosophila MelanogasterGiant Fiber SystemIn Vivo ActivityPharmacological AgentsModulatory EffectsNeuronal CircuitSmall MoleculesPeptidesMolecular TargetsGap JunctionsCholinergicNicotinic Acetylcholine ReceptorsNeuromuscular JunctionsGlutamatergicNanoliter QuantitiesIntracellular Recordings

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

从巨纤维通路的电生理记录 D。果蝇</em

成人整装准备果蝇巨纤维染料注射腹侧神经索

标记的单细胞在中枢神经系统<em>果蝇</em

在自发活动的测定<em>果蝇</em

简单的检测方法的社交回避的量化<em>果蝇</em

在气味引导行为的高分辨率定量<em>果蝇</em>使用<em> Flywalk</em>范式

一个行为分析对机械感觉MARCM为基础的克隆<em>果蝇</em

高通量检测，以检查个体产蛋首<em>果蝇</em

一个简单的方法来衡量在改建悬赏寻求行为使用<em>果蝇</em

毛细管馈线分析测量的摄食<em>果蝇</em

Read Article