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Nanoinjection paires et test d'électrophysiologie à l'écran de la bioactivité des composés en utilisant le Drosophila melanogaster Système de fibre géant
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Neuroscience
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JoVE Journal Neuroscience
Paired Nanoinjection and Electrophysiology Assay to Screen for Bioactivity of Compounds using the Drosophila melanogaster Giant Fiber System
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Nanoinjection paires et test d'électrophysiologie à l'écran de la bioactivité des composés en utilisant le Drosophila melanogaster Système de fibre géant

12,968 Views

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09:39 min

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April 15, 2012

DOI:

10.3791/3597-v

DOI:
10.3791/3597-v

•

09:39 min
April 15, 2012

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1 Views
, , , ,
1Department of Biological Sciences,Florida Atlantic University, 2Department of Chemistry & Biochemistry,Florida Atlantic University

Tags

NanoinjectionElectrophysiology AssayScreenBioactivityCompoundsDrosophila MelanogasterGiant Fiber SystemIn Vivo ActivityPharmacological AgentsModulatory EffectsNeuronal CircuitSmall MoleculesPeptidesMolecular TargetsGap JunctionsCholinergicNicotinic Acetylcholine ReceptorsNeuromuscular JunctionsGlutamatergicNanoliter QuantitiesIntracellular Recordings

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Mejia, M., Heghinian, M. D., Busch, A., Marí, F., Godenschwege, T. A. Paired Nanoinjection and Electrophysiology Assay to Screen for Bioactivity of Compounds using the Drosophila melanogaster Giant Fiber System. J. Vis. Exp. (62), e3597, doi:10.3791/3597 (2012).

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