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Análise de Morfologia Spine dendríticas em neurônios cultivados CNS
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Neuroscience
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JoVE Journal Neuroscience
Analysis of Dendritic Spine Morphology in Cultured CNS Neurons

Análise de Morfologia Spine dendríticas em neurônios cultivados CNS

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34,598 Views

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11:48 min

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July 13, 2011

DOI:

10.3791/2794-v

DOI:
10.3791/2794-v

•

11:48 min
July 13, 2011

•

10 Views
, ,
1Department of Physiology,Northwestern University Feinberg School of Medicine, 2Department of Psychiatry and Behavioral Sciences,Northwestern University Feinberg School of Medicine

Summary

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Numerosos estudos recentes identificaram mutações em proteínas sinápticas associada a patologias cerebrais. Primários cultivados neurônios corticais oferecem grande flexibilidade para examinar os efeitos destas proteínas doenças associadas na morfologia e motilidade espinha dendrítica.

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Srivastava, D. P., Woolfrey, K. M., Penzes, P. Analysis of Dendritic Spine Morphology in Cultured CNS Neurons. J. Vis. Exp. (53), e2794, doi:10.3791/2794 (2011).

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