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Biomoleculaire Detectie gebruik de interferometrische reflectie Imaging Sensor (IRIS)
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Biomolecular Detection employing the Interferometric Reflectance Imaging Sensor (IRIS)
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Biomoleculaire Detectie gebruik de interferometrische reflectie Imaging Sensor (IRIS)

Nederlands

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14,362 Views

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11:04 min

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May 03, 2011

DOI:

10.3791/2694-v

DOI:
10.3791/2694-v

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11:04 min
May 03, 2011

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1 Views
, , , , , , , , , , , , ,
1Department of Electrical and Computer Engineering,Boston University , 2Department of Biomedical Engineering,Boston University , 3Center for Advanced Genomics Technology,Boston University , 4Department of Medicine, Section of Infectious Diseases,Boston University School of Medicine, 5Department of Microbiology,Boston University School of Medicine, 6CNR (National Research Council),Istituto di Chimica del Riconoscimento Molecolare

Summary

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Kwantitatieve, high-throughput, real-time, en label-free biomoleculaire detectie (DNA, eiwitten, enz.) op SiO<sub> 2</sub> Oppervlakken kunnen worden bereikt met behulp van een eenvoudige interferometrische techniek die is gebaseerd op LED-verlichting, minimale optische componenten, en een camera. De Interferometrische reflectie Imaging Sensor (IRIS) is goedkoop, eenvoudig te gebruiken, en vatbaar voor formats microarray.

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Biomolecular DetectionInterferometric Reflectance Imaging Sensor (IRIS)Biomolecular InteractionsDiagnostic ApplicationsProteomic BiomarkersGenomic BiomarkersMolecular AffinitiesMolecular SpecificitiesLabelsImmunoassaysEnzyme-linked Immunosorbent Assay (ELISA)Polymerase Chain Reaction (PCR)Gel Electrophoresis AssaysMass Spectrometry (MS)Label-free Methods

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Cite this Article

Lopez, C. A., Daaboul, G. G., Ahn, S., Reddington, A. P., Monroe, M. R., Zhang, X., Irani, R. J., Yu, C., Genco, C. A., Cretich, M., Chiari, M., Goldberg, B. B., Connor, J. H., Ünlü, M. S. Biomolecular Detection employing the Interferometric Reflectance Imaging Sensor (IRIS). J. Vis. Exp. (51), e2694, doi:10.3791/2694 (2011).

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