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マウスにおける自発脳内出血をモデル化する自家血注入

JoVE Journal
Neuroscience

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JoVE Journal Neuroscience

Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice

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マウスにおける自発脳内出血をモデル化する自家血注入

14,511 Views

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07:02 min

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August 24, 2011

DOI:

DOI:

•

07:02 min

August 24, 2011

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5 Views

Lauren H. Sansing^1,2,3, Scott E. Kasner², Louise McCullough¹, Puneet Agarwal², Frank A. Welsh⁴, Katalin Kariko⁴

¹Department of Neurology,University of Connecticut Health Center, ²Department of Neurology,School of Medicine, University of Pennsylvania, ³Department of Neurosurgery,Hartford Hospital, ⁴Department of Neurosurgery,School of Medicine, University of Pennsylvania

Summary

このプロトコルで説明されているマウスの脳内出血の自家血注入モデルでは、針のトラックまでの血液逆流、ポンプシステムにおける無抗凝固剤のリスクを最小限に抑えるために二重注入の技術を使用し、システム内のすべてのデッドスペースと拡張可能なチューブを排除。

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