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Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice
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Neuroscience
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JoVE Journal Neuroscience
Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice

Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice

English

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14,507 Views

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07:02 min

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August 24, 2011

DOI:

10.3791/2618-v

DOI:
10.3791/2618-v

•

07:02 min
August 24, 2011

•

5 Views
, , , , ,
1Department of Neurology,University of Connecticut Health Center, 2Department of Neurology,School of Medicine, University of Pennsylvania, 3Department of Neurosurgery,Hartford Hospital, 4Department of Neurosurgery,School of Medicine, University of Pennsylvania

Summary

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The autologous blood injection model of intracerebral hemorrhage in mice described in this protocol uses the double injection technique to minimize risk of blood reflux up the needle track, no anticoagulants in the pumping system, and eliminates all dead space and expandable tubing in the system.

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Cite this Article

Sansing, L. H., Kasner, S. E., McCullough, L., Agarwal, P., Welsh, F. A., Kariko, K. Autologous Blood Injection to Model Spontaneous Intracerebral Hemorrhage in Mice. J. Vis. Exp. (54), e2618, doi:10.3791/2618 (2011).

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