'Dergi'
/
Biyokimya
/
In Silico Structural Analysis of Protein Carbonylation by Lipid Derivatives
/
Author Spotlight: In Silico Creation and Impact of Carbonylated Amino Acids on Protein Structure and Function
JoVE Journal
Biyokimya
Author Produced
'Bu içeriği görüntülemek için JoVE aboneliği gereklidir.'  'Oturum açın veya ücretsiz deneme sürümünü başlatın.'
JoVE Journal Biyokimya
Synthesizing Amino Acids Modified with Reactive Carbonyls in Silico to Assess Structural Effects Using Molecular Dynamics Simulations

Author Spotlight: In Silico Creation and Impact of Carbonylated Amino Acids on Protein Structure and Function

In Silico Structural Analysis of Protein Carbonylation by Lipid Derivatives

DOI:
10.3791/66605-v

•

01:55 min

•

April 26, 2024

•

, , , , ,
1Analytical Chemistry and Biomedicine Group, Exact and Natural Sciences Faculty,University of Cartagena, 2Analytical Chemistry and Biomedicine Group, Pharmaceutical Sciences Faculty,University of Cartagena, 3Pharmacology and Therapeutics Research Group,University of Cartagena

'Etiketler'

Protein CarbonylationReactive Carbonyl SpeciesLipid Peroxidation4-hydroxy-2-nonenal (HNE)4-hydroxy-2-hexenal (HHE)4-Oxo-2-nonenal (ONE)Malondialdehyde (MDA)Molecular Dynamics SimulationsStructural ChangesAmino Acid ModificationThioredoxinBovine Serum AlbuminZu-5-ankyrin Domain

Embed

'ÇALMA LİSTESİNE EKLE'

Usage Statistics

'İlgili Videolar'

Author Spotlight: In Silico Creation and Impact of Carbonylated Amino Acids on Protein Structure and Function

Computational Design and Energy Optimization of Modified Amino Acids Reacting with Lipid Peroxidation Aldehydes

Parameterization of Modified Amino Acid Residues into the Thioredoxin Protein Structure

Read Article