Journal
/
Bioquímica
/
In Silico Structural Analysis of Protein Carbonylation by Lipid Derivatives
/
Author Spotlight: In Silico Creation and Impact of Carbonylated Amino Acids on Protein Structure and Function
JoVE Revista
Bioquímica
Author Produced
Se requiere una suscripción a JoVE para ver este contenido.  Inicie sesión o comience su prueba gratuita.
JoVE Revista Bioquímica
Synthesizing Amino Acids Modified with Reactive Carbonyls in Silico to Assess Structural Effects Using Molecular Dynamics Simulations

Author Spotlight: In Silico Creation and Impact of Carbonylated Amino Acids on Protein Structure and Function

118 Views

•

01:55 min

•

April 26, 2024

DOI:

10.3791/66605-v

DOI:
10.3791/66605-v

•

01:55 min
April 26, 2024

•

7 Views
, , , , ,
1Analytical Chemistry and Biomedicine Group, Exact and Natural Sciences Faculty,University of Cartagena, 2Analytical Chemistry and Biomedicine Group, Pharmaceutical Sciences Faculty,University of Cartagena, 3Pharmacology and Therapeutics Research Group,University of Cartagena

Explore More Videos

Protein CarbonylationReactive Carbonyl SpeciesLipid Peroxidation4-hydroxy-2-nonenal (HNE)4-hydroxy-2-hexenal (HHE)4-Oxo-2-nonenal (ONE)Malondialdehyde (MDA)Molecular Dynamics SimulationsStructural ChangesAmino Acid ModificationThioredoxinBovine Serum AlbuminZu-5-ankyrin Domain

Read Article

Cite this Article

Pineda-Alemán, R., Cabarcas-Herrera, C., Alviz-Amador, A., Pérez-Gonzalez, H., Rodríguez-Cavallo, E., Méndez-Cuadro, D. Synthesizing Amino Acids Modified with Reactive Carbonyls in Silico to Assess Structural Effects Using Molecular Dynamics Simulations . J. Vis. Exp. (206), e66605, doi:10.3791/66605 (2024).

Download .ris file

Copy

Share Video

.

Copy