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The Automated Crystallography Pipelines at the EMBL HTX Facility in Grenoble
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The Automated Crystallography Pipelines at the EMBL HTX Facility in Grenoble

The Automated Crystallography Pipelines at the EMBL HTX Facility in Grenoble

DOI:
10.3791/62491-v

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06:50 min

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June 05, 2021

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, , , , , , , , , ,
1European Molecular Biology Laboratory, 2ALPX S.A.S., 3Institut de Biologie Structurale

Bölümler

  • 00:04Introduction
  • 00:32Crystallization Screening Experiments
  • 02:42Crystal Optimization Experiments
  • 03:18Crystal Harvesting and Tracking
  • 04:21Synchrotron X-Ray Diffraction Experiments
  • 05:27Sonuçlar
  • 06:08Conclusion

Özet

Otomatik Çeviri

Otomatik Çeviri

Here, we describe how to use the automated macromolecular crystallography pipelines for protein-to-structure, rapid ligand-protein complex analysis and large-scale fragment screening based on the CrystalDirect technology at the HTX Laboratory in EMBL Grenoble.

Etiketler

Automated CrystallographyEMBL HTX FacilityGrenobleCrystalDirect TechnologyCRIM SoftwareCrystal Graphic Information Management SystemCrystallization ProtocolCrystallization ScreensHigh Throughput Crystallization LabAutomated ImagersCRIMSCrystallization PlatesCrystallization ExperimentsCrystal HarvestingProtein Structure DeterminationFragment ScreeningLigand Screening

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