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The Automated Crystallography Pipelines at the EMBL HTX Facility in Grenoble
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June 05, 2021
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Here, we describe how to use the automated macromolecular crystallography pipelines for protein-to-structure, rapid ligand-protein complex analysis and large-scale fragment screening based on the CrystalDirect technology at the HTX Laboratory in EMBL Grenoble.
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Automated CrystallographyEMBL HTX FacilityGrenobleCrystalDirect TechnologyCRIM SoftwareCrystal Graphic Information Management SystemCrystallization ProtocolCrystallization ScreensHigh Throughput Crystallization LabAutomated ImagersCRIMSCrystallization PlatesCrystallization ExperimentsCrystal HarvestingProtein Structure DeterminationFragment ScreeningLigand Screening
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Cornaciu, I., Bourgeas, R., Hoffmann, G., Dupeux, F., Humm, A., Mariaule, V., Pica, A., Clavel, D., Seroul, G., Murphy, P., Márquez, J. A. The Automated Crystallography Pipelines at the EMBL HTX Facility in Grenoble. J. Vis. Exp. (172), e62491, doi:10.3791/62491 (2021).
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