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Biochemistry

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JoVE Journal Biochemistry
The Automated Crystallography Pipelines at the EMBL HTX Facility in Grenoble
 

The Automated Crystallography Pipelines at the EMBL HTX Facility in Grenoble

Article DOI: 10.3791/62491-v • 06:50 min • June 5th, 2021
June 5th, 2021 •
1,2, 1, 1, 1,3, 1, 1, 1,2, 1,2, 1,2, 1, 1,2
1European Molecular Biology Laboratory, 2ALPX S.A.S., 3Institut de Biologie Structurale

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Here, we describe how to use the automated macromolecular crystallography pipelines for protein-to-structure, rapid ligand-protein complex analysis and large-scale fragment screening based on the CrystalDirect technology at the HTX Laboratory in EMBL Grenoble.

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Keywords: Automated Crystallography EMBL HTX Facility Grenoble CrystalDirect Technology CRIM Software Crystal Graphic Information Management System Crystallization Protocol Crystallization Screens High Throughput Crystallization Lab Automated Imagers CRIMS Crystallization Plates Crystallization Experiments Crystal Harvesting Protein Structure Determination Fragment Screening Ligand Screening
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