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一种新的坏死性肠结肠炎人上皮肠素模型
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JoVE Journal İmmünoloji ve Enfeksiyon
A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis
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一种新的坏死性肠结肠炎人上皮肠素模型

7,510 Views

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08:42 min

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April 10, 2019

DOI:

10.3791/59194-v

DOI:
10.3791/59194-v

•

08:42 min
April 10, 2019

•

4 Views
, , , ,
1Pediatri Anabilim Dalı,Northwestern University, 2Division of Pediatric Surgery,Ann & Robert H. Lurie Children’s Hospital of Chicago

Özet

Automatically generated

肠类正在成为人类疾病研究的新模式。该协议描述了如何模拟人坏死性小肠结肠炎的肠素模型使用脂多糖 (LPS) 治疗从新生儿组织产生的肠内化合物。收集的肠素显示炎症变化类似于那些在人类坏死性小肠结肠炎。

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Cite this Article

Ares, G. J., Buonpane, C., Yuan, C., Wood, D., Hunter, C. J. A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis. J. Vis. Exp. (146), e59194, doi:10.3791/59194 (2019).

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