/
/
A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis
Bu içeriği görüntülemek için JoVE aboneliği gereklidir. Oturum açın veya ücretsiz deneme sürümünü başlatın.
A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis
7,512 Views
•
08:42 min
•
April 10, 2019
DOI:
Özet
Automatically generated
Enteroids are emerging as a novel model in the study of human disease. The protocol describes how to simulate an enteroid model of human necrotizing enterocolitis using lipopolysaccharide (LPS) treatment of enteroids generated from neonatal tissue. Collected enteroids demonstrate inflammatory changes akin to those seen in human necrotizing enterocolitis.
Read Article
Cite this Article
Ares, G. J., Buonpane, C., Yuan, C., Wood, D., Hunter, C. J. A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis. J. Vis. Exp. (146), e59194, doi:10.3791/59194 (2019).
Copy