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منهجية الاصطناعية لغير المتماثلة الفيروسين المستمدة الأنظمة الحيوية المزدوجة عبر الصلبة منهجية تستند الراتنج المرحلة
JoVE Journal
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JoVE Journal Kimya
Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
DOI:

07:07 min

March 12, 2015

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'Bölümler'

  • 00:05'Başlık'
  • 01:26Synthesis of Biotin-Fc-cysteine
  • 04:46Characterization of Biotin-Fc-cysteine and Immobilization on a Gold Surface
  • 05:56Results: Synthesis and Immobilization of Biotin-Fc-cysteine on a Gold Surface
  • 06:32Conclusion

Özet

'Otomatik Çeviri'

The synthesis of asymmetric species of ferrocene is challenging using solution techniques. This report focuses on the methods carried out to produce a ferrocene-biotin bioconjugate using facile and clean reactions accomplished via solid-phase synthesis. Incorporation of a thiolate moiety is shown to impart the ability for immobilization on gold surfaces.

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