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Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology
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JoVE Journal 化学
Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology

Synthetic Methodology for Asymmetric Ferrocene Derived Bio-conjugate Systems via Solid Phase Resin-based Methodology

DOI:
10.3791/52399-v

•

07:07 min

•

March 12, 2015

•

, , ,
1化学科,Texas Christian University

章

  • 00:05標題
  • 01:26Synthesis of Biotin-Fc-cysteine
  • 04:46Characterization of Biotin-Fc-cysteine and Immobilization on a Gold Surface
  • 05:56Results: Synthesis and Immobilization of Biotin-Fc-cysteine on a Gold Surface
  • 06:32Conclusion

概要

自動翻訳

自動翻訳

The synthesis of asymmetric species of ferrocene is challenging using solution techniques. This report focuses on the methods carried out to produce a ferrocene-biotin bioconjugate using facile and clean reactions accomplished via solid-phase synthesis. Incorporation of a thiolate moiety is shown to impart the ability for immobilization on gold surfaces.

タグ

FerroceneBiotinBioconjugateBiosensorSolid-phase SynthesisEarly Disease Detection

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