Metodologia sintetico per Asymmetric Ferrocene derivati ​​sistemi bio-coniugati attraverso Solid Metodologia Resina a base di fase

The synthesis of asymmetric species of ferrocene is challenging using solution techniques. This report focuses on the methods carried out to produce a ferrocene-biotin bioconjugate using facile and clean reactions accomplished via solid-phase synthesis. Incorporation of a thiolate moiety is shown to impart the ability for immobilization on gold surfaces.