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Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition
1Division of Biology,California Institute of Technology, 2Solomon H. Snyder Department of Neuroscience, Neurology, and Ophthalamology,Johns Hopkins University School of Medicine, 3Department of Radiation Oncology & Molecular Radiation Sciences,Johns Hopkins University School of Medicine, 4Radyasyon Onkoloji Bölümü,University Of Washington Medical Center, 5Institute for Cell Engineering and High-Throughput Biology Center,Johns Hopkins University School of Medicine
Bölümler
- 00:05Başlık
- 01:59Calibration of the CT-guided Laser Platform: Part 1
- 04:15Calibration of the CT-guided Laser Platform: Part 2
- 06:36Preparation of Mouse Subjects for Focal Irradiation
- 08:37Calibration and Experimental Findings
- 11:12Conclusion
The function of adult-born mammalian neurons remains an active area of investigation. Ionizing radiation inhibits the birth of new neurons. Using computer tomography-guided focal irradiation (CFIR), three-dimensional anatomical targeting of specific neural progenitor populations can now be used to assess the functional role of adult neurogenesis.
